datum (n=1)<p><strong>Most interesting detail: "we detected the virus passing from one sinus at the peak of infection to the other a few days later"</strong></p><p>Model animals: "cynomolgus macaques"</p><p>They also evaluated "two convalescent animals [...] exposed to the SARS-CoV-2 Delta variant three months prior" and found "no major uptake by the nasal cavity" but "detection of the PET signal for SARS-CoV-2 spike antigen up to three months post initial infection in the lungs and brains"</p><p>"local accumulation [...] in areas of the brain [...] consistent with previous findings of neuroinflammation in humans infected with SARS-CoV-2 and in rhesus macaques up to six weeks after SARS-CoV-2 infection. The localized crossing of the blood-brain barrier (BBB) by the radiotracer in convalescent animals can be explained by thrombo-inflammation previously reported in patients with active long-COVID."</p><p><a href="https://www.nature.com/articles/s41467-025-58173-y" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41467-025</span><span class="invisible">-58173-y</span></a></p><p>h/t <span class="h-card" translate="no"><a href="https://zeroes.ca/@EricCarroll" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>EricCarroll</span></a></span> </p><p><a href="https://zeroes.ca/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SARSCoV2</span></a> <a href="https://zeroes.ca/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID19</span></a> <a href="https://zeroes.ca/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>COVID</span></a> <a href="https://zeroes.ca/tags/CovidIsNotOver" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidIsNotOver</span></a> <a href="https://zeroes.ca/tags/CovidCompetent" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidCompetent</span></a> <a href="https://zeroes.ca/tags/AirborneAware" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AirborneAware</span></a></p>