#electronmicroscopy

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StructBiolCommunicationsSafer, nonradioactive staining alternatives for electron microscopy are introduced, simplifying sample preparation, reducing costs and making structural biology more accessible to researchers globally <a href="https://mstdn.science/tags/NegativeStaining" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NegativeStaining</a> <a href="https://mstdn.science/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a> <a href="https://doi.org/10.1107/S2053230X24011294" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://doi.org/10.1107/S2053230X24011294</a>

Stephen RoyleMitochondria talking to ER. I wonder what they're saying?<a href="https://biologists.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://biologists.social/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a>

Albert CardonaIf an <a href="https://mathstodon.xyz/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a> engineer would like to join us at the <a href="https://mathstodon.xyz/tags/MRCLMB" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MRCLMB</a> to implement this beam-shifting GridTape TEM approach, send me an email. We have two JEOL TEMs to tinker with.

Albert CardonaGridTape TEM with beam deflection to reduce stage movements and increase imaging throughput:"Fast imaging of millimeter-scale areas with beam deﬂection transmission electron microscopy", Zhao et al. 2024<a href="https://www.nature.com/articles/s41467-024-50846-4" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.nature.com/articles/s41467-024-50846-4</a><a href="https://mathstodon.xyz/tags/TEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#TEM</a> <a href="https://mathstodon.xyz/tags/GridTapeTEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GridTapeTEM</a> <a href="https://mathstodon.xyz/tags/vEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vEM</a> <a href="https://mathstodon.xyz/tags/VolumeEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#VolumeEM</a> <a href="https://mathstodon.xyz/tags/connectomics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#connectomics</a> <a href="https://mathstodon.xyz/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mathstodon.xyz/tags/microscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microscopy</a> <a href="https://mathstodon.xyz/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a>

Furqan ShahIf you were wondering how <a href="https://mstdn.science/tags/dental" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dental</a> <a href="https://mstdn.science/tags/enamel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#enamel</a> resists years of damage and wear, the "enamel rods" are tightly packed, long structures composed of hydroxy(l)apatite nanowires. This highly organized pattern of enamel rods achieves exceptional durability and resistance to mechanical stress.<a href="https://mstdn.science/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://mstdn.science/tags/biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biology</a> <a href="https://mstdn.science/tags/tooth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tooth</a> <a href="https://mstdn.science/tags/biomineralization" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomineralization</a> <a href="https://mstdn.science/tags/mineral" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mineral</a> <a href="https://mstdn.science/tags/apatite" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#apatite</a> <a href="https://mstdn.science/tags/nano" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nano</a> <a href="https://mstdn.science/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#medicine</a> <a href="https://mstdn.science/tags/health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#health</a> <a href="https://mstdn.science/tags/biomaterials" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomaterials</a> <a href="https://mstdn.science/tags/electronmicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#electronmicroscopy</a> <a href="https://mstdn.science/tags/imaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#imaging</a>

Emilia Jarochowska 🇺🇦🌱It's very satisfying to see the crown article of my first PhD student Bryan Shirley published! Skeleton is usually all that remains from an animal in the fossil record, so in order to find out how the animal functioned when alive, we have to squeeze out clues from the skeletal tissues, for example using advanced <a href="https://circumstances.run/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a> 🔬. We were told that vertebrate tissues are too chemically unstable to study this way, but with the help of experts in microscopy, we were able to make rapid measurements of crystallography in the oldest <a href="https://circumstances.run/tags/vertebrate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vertebrate</a> hashtag#teeth to understand how they function evolved. Turns out the crystal orientation reflects the function! From the <a href="https://circumstances.run/tags/ultrastructure" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ultrastructure</a> we can estimate how the animals were biting and see their evolutionary adaptations at the level of individual crystals 💎 This was possible thanks to the facilities and funding by EXCITE network and Deutsche Forschungsgemeinschaft (DFG) - German Research Foundation Now published <a href="https://circumstances.run/tags/OpenAccess" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#OpenAccess</a> at <a href="https://rdcu.be/dLpbD" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://rdcu.be/dLpbD</a> <a href="https://circumstances.run/tags/UtrechtUniversity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UtrechtUniversity</a> <a href="https://circumstances.run/tags/evolution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#evolution</a> <a href="https://circumstances.run/tags/biomineralization" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomineralization</a> <a href="https://circumstances.run/tags/paleontology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#paleontology</a> <a href="https://circumstances.run/tags/paleobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#paleobiology</a> <a href="https://circumstances.run/tags/conodonts" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#conodonts</a>

Lukas VFN 🇪🇺Discovery of the first <a href="https://scholar.social/tags/fractal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#fractal</a> molecule in nature <a href="https://phys.org/news/2024-04-discovery-fractal-molecule-nature.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2024-04-discovery-fractal-molecule-nature.html</a>Emergence of fractal geometries in the <a href="https://scholar.social/tags/evolution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#evolution</a> of a metabolic <a href="https://scholar.social/tags/enzyme" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#enzyme</a>: Franziska Sendker et al. <a href="https://www.nature.com/articles/s41586-024-07287-2" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.nature.com/articles/s41586-024-07287-2</a>"They discovered a <a href="https://scholar.social/tags/microbial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microbial</a> enzyme—citrate synthase from <a href="https://scholar.social/tags/cyanobacteria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cyanobacteria</a>—that spontaneously assembles into a pattern known as the <a href="https://scholar.social/tags/SierpinskiTriangle" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SierpinskiTriangle</a>. <a href="https://scholar.social/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a> and evolutionary <a href="https://scholar.social/tags/biochemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biochemistry</a> studies indicate that this fractal may represent an evolutionary accident."

Furqan Shah🧪🔬🦴💠 Transformation of bone mineral morphology: From discrete marquise-shaped motifs to a continuous interwoven mesh<a href="https://doi.org/10.1016/j.bonr.2020.100283" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://doi.org/10.1016/j.bonr.2020.100283</a><a href="https://mstdn.science/tags/bone" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bone</a> <a href="https://mstdn.science/tags/biomineralization" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomineralization</a> <a href="https://mstdn.science/tags/biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biology</a> <a href="https://mstdn.science/tags/osteocyte" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#osteocyte</a> <a href="https://mstdn.science/tags/collagen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#collagen</a> <a href="https://mstdn.science/tags/apatite" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#apatite</a> <a href="https://mstdn.science/tags/mineral" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mineral</a> <a href="https://mstdn.science/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://mstdn.science/tags/electronmicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#electronmicroscopy</a> <a href="https://mstdn.science/tags/Ramanspectroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Ramanspectroscopy</a> <a href="https://mstdn.science/tags/imaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#imaging</a>

Jan BVarious cool <a href="https://mastodon.social/tags/SEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SEM</a> images I have taken during my master thesis:These are ZnO <a href="https://mastodon.social/tags/nanowires" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nanowires</a> on a ZnO layer. The wires have a diameter 300 times smaller than a human hair.Normally they should be attached to the silicon substrate, but a scratch caused this cool looking damage to the sample.ZnO nanowires have cool properties, for example each wire can work as its own tiny laser under the right conditions. <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://mastodon.social/tags/physics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#physics</a> <a href="https://mastodon.social/tags/physik" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#physik</a> <a href="https://mastodon.social/tags/nanowires" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nanowires</a> <a href="https://mastodon.social/tags/nanotechnology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nanotechnology</a> <a href="https://mastodon.social/tags/nano" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nano</a> <a href="https://mastodon.social/tags/microscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microscopy</a> <a href="https://mastodon.social/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a>

Furqan Shah2/3; <a href="https://mstdn.science/tags/Introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Introduction</a> 🕰️ - My scholarly interests [‼️] include <a href="https://mstdn.science/tags/bone" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bone</a> repair <a href="https://mstdn.science/tags/biomaterials" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomaterials</a>, the <a href="https://mstdn.science/tags/osteocyte" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#osteocyte</a> (a remarkable cell in bone), <a href="https://mstdn.science/tags/osseointegration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#osseointegration</a> of implants, <a href="https://mstdn.science/tags/biomineralization" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomineralization</a>. I think <a href="https://mstdn.science/tags/bacteria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bacteria</a> are fascinating! <a href="https://mstdn.science/tags/electronmicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#electronmicroscopy</a> and <a href="https://mstdn.science/tags/Ramanspectroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Ramanspectroscopy</a> ftw! <a href="https://mstdn.science/tags/academia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#academia</a> <a href="https://mstdn.science/tags/academicchatter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#academicchatter</a> <a href="https://mstdn.science/tags/AcademicMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AcademicMastodon</a> <a href="https://mstdn.science/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Science</a> <a href="https://mstdn.science/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a> <a href="https://mstdn.science/tags/phd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#phd</a> <a href="https://mstdn.science/tags/mosstodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mosstodon</a> <a href="https://mstdn.science/tags/icetodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#icetodon</a> <a href="https://mstdn.science/tags/Fediverse" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Fediverse</a> <a href="https://mstdn.science/tags/nature" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nature</a>

Albert Cardona"SmartEM: machine-learning guided electron microscopy" by Meirovitch et al 2023 (Nir Shavit and Aravi Samuel labs) <a href="https://www.biorxiv.org/content/10.1101/2023.10.05.561103v1.abstract" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.biorxiv.org/content/10.1101/2023.10.05.561103v1.abstract</a>Turn up the imaging rate of your scanning electron microscope by only imaging at high resolution the areas of the image necessary to resolve ambiguities in the low-res image. Motivated by the need for high-throughput but inexpensive imaging for <a href="https://mathstodon.xyz/tags/connectomics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#connectomics</a>.<a href="https://mathstodon.xyz/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mathstodon.xyz/tags/vEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vEM</a> <a href="https://mathstodon.xyz/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a>

eLifeThe tool MorphoFeatures lets researchers automatically assign cell types and tissues in <a href="https://fediscience.org/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a> images, a step which is critical for understanding complex organisms. <a href="https://fediscience.org/tags/12DaysOfeLife" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#12DaysOfeLife</a> <a href="https://elifesciences.org/articles/80918?utm_source=mastodon&utm_medium=social&utm_campaign=organic_12Days" rel="nofollow noopener noreferrer" target="_blank">https://elifesciences.org/articles/80918?utm_source=mastodon&utm_medium=social&utm_campaign=organic_12Days</a>

SBGridNew Title Alert: MemBrain-Seg is new to the <a href="https://mstdn.science/tags/SBGrid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SBGrid</a> software collection. This is a Python project developed by teamtomo for membrane segmentation in 3D for cryo-electron tomography (cryo-ET). This tool aims to provide researchers with an efficient and reliable method for segmenting membranes in 3D microscopic images.<a href="https://github.com/teamtomo/membrain-seg" rel="nofollow noopener noreferrer" target="_blank">https://github.com/teamtomo/membrain-seg</a><a href="https://mstdn.science/tags/electronmicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#electronmicroscopy</a> <a href="https://mstdn.science/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://mstdn.science/tags/cryo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cryo</a>-ET <a href="https://mstdn.science/tags/membranes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#membranes</a>

Stephen RoyleThe images in this paper published last year by the Svitkina group are amazing. Look at this microtubule/actin/clathrin love in at the plasma membrane! <a href="https://biologists.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://biologists.social/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a> <a href="https://biologists.social/tags/Microscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Microscopy</a> <a href="https://biologists.social/tags/Cytoskeleton" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Cytoskeleton</a> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576739/" rel="nofollow noopener noreferrer" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9576739/</a>

Breaking Taps3ax accelerometer/gyro chip. Composite of 3 different chips that I decapped. Didn't get a complete view of top right unfortunately.I thought the bottom was accel at first, but thinking they are gyros now? Dual mass vibrating kind? Lack of combs on the top devices is throwing me, just a few plates that I can see.There are "pits" or cutouts under two of the three devices under the bottom, which is contributing to my feeling they are gyros (to help allow coriolis distortion)<a href="https://universeodon.com/tags/mems" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mems</a> <a href="https://universeodon.com/tags/decapping" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#decapping</a> <a href="https://universeodon.com/tags/gyroscope" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#gyroscope</a> <a href="https://universeodon.com/tags/accelerometer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#accelerometer</a> <a href="https://universeodon.com/tags/sem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sem</a> <a href="https://universeodon.com/tags/electronmicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#electronmicroscopy</a>

Breaking TapsEver wanted to see a Goldenrod plant and pollen up close? Now you can! 🙂 SEM analysis of the common goldenrod (Solidago) plant that I harvested/preserved over the summer. My plant biology knowledge is patchy, but I don't think I made too many mistakes in the narration (please feel free to correct if I did though!)<a href="https://www.youtube.com/watch?v=gCIGS2HX_PY" rel="nofollow noopener noreferrer" target="_blank">https://www.youtube.com/watch?v=gCIGS2HX_PY</a><a href="https://universeodon.com/tags/botany" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#botany</a> <a href="https://universeodon.com/tags/sem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sem</a> <a href="https://universeodon.com/tags/electronmicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#electronmicroscopy</a> <a href="https://universeodon.com/tags/goldenrod" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#goldenrod</a> <a href="https://universeodon.com/tags/Gardening" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Gardening</a> <a href="https://universeodon.com/tags/NativePlants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NativePlants</a> <a href="https://universeodon.com/tags/wildflower" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#wildflower</a> <a href="https://universeodon.com/tags/Ecology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Ecology</a> <a href="https://universeodon.com/tags/solidago" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#solidago</a>

Stephen RoyleHello there smiley mitochondrion! <a href="https://mastodon.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://mastodon.social/tags/ElectronMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMicroscopy</a>

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