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Auf dieser sehr nervigen Website habe ich einen #Schnelltest für 9 (!) Erkältungskrankheiten gefunden.

shop-apotheke.com/sanitaetshau

Angeblich ist der zur „qualitativen in-vitro-Detektion von Antigenen des #SARS-CoV-2, Mycoplasma pneumoniae, des Respiratorischen Synzytial virus, der Parainfluenzaviren (Typen 1, 2 und 3), des Humanen Metapneumovirus, des Adenovirus sowie der Influenza A und B in Nasen- und Nasopharynxabstrichen“

Am billigsten ist die 10 Stück Packung für 20€.

Bin mal gespannt, ob das Zeug taugt & Falls Sie eine Idee hat, wie man das testet, gerne her damit.

www.shop-apotheke.comDvot Multiplex-Testkit auf 9 Atemwegsinfektionen (9in1) 10 St - Shop ApothekeDvot Multiplex-Testkit auf 9 Atemwegsinfektionen (9in1) 10 St für nur € 20,26 bei Ihrer Online Apotheke für Deutschland kaufen.

🇩🇪

CN #SARS #CovidIsNotOver #Corona #LongCovid #MECFS #Covid19

Da die offiziellen Zahlen zum aktuellen Infektionsgeschehen um Größenordnungen zu niedrig kommuniziert werden, habe ich für Deutschland und die einzelnen Bundesländer ein Dashboard mit einer Schätzung der realen Zahlen auf Basis der Hospitalisierungen und kalibriert mit Abwasserdaten entwickelt.

Die Daten werden täglich und automatisch aktualisiert.

Weitere Informationen unter:

covidisnotover.info/aktuelle-c

"A French team has recently teased some brand new findings — as yet unpublished — saying they know where the virus has been hiding. ... have found #SARS-nCov-2 hiding in a special type of immune cell called #megakaryocytes. These cells produce the little clotting factors in blood called platelets and — can seed the virus into the platelets. If that leads to problems with blood flow, it could explain many of the problems in #LongCovid, including fatigue and brain fog."
crikey.com.au/2024/12/02/long-

Crikey · Long COVID is becoming a serious social and economic issue for AustraliaBy Jason Murphy

Cross - #neutralization of #Influenza A by #SARS-CoV-2 specific neutralizing #antibodies and polyclonal #plasma: Is pre-exposure to SARS-CoV-2 protective against Influenza A? Heliyon, cell.com/heliyon/fulltext/S240

This #investigation revealed that neutralizing antibodies of #delta #variant cross-reacted with the Influenza A virus, which might protect against influenza viruses and reduce and shift the seasonal influenza circulation during the COVID-19 pandemic.

Another great pre-print from the Killian Schober lab and accompanying tweetorial:
biorxiv.org/content/10.1101/20
x.com/kischober/status/1852222
It always feels like Xmas day when I see one of their publications. In this one, they followed the clonotypic and phenotypic dynamics of antigen-specific #Tcells from #SARS-CoV2 vaccinated individuals and found that peripheral clonotype expansion was more probabilistic than avidity driven. #immunology

bioRxiv · Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidityWhile the quantity of vaccination-induced T cells represents a routine immunogenicity parameter, the quality of such responses is poorly understood. We here report on a clinical cohort of 29 human healthy individuals who received three mRNA vaccinations against SARS-CoV-2 before any breakthrough infection. We characterized the magnitude, phenotype and clonal composition of CD8 T cell responses against 16 epitope specificities by ELISpot, flow cytometry as well as single-cell RNA, TCR and surface protein sequencing. To test the functionality of identified clonotypes, 106 T cell receptors (TCR) from five epitope-specific repertoires were re-expressed and tested for peptide sensitivity. While recruited repertoires were overall enriched for high-avidity TCRs, differential clonal expansion was not linked to fine avidity differences. Instead, maintenance of polyclonality ensured robustness in counteracting mutational escape of epitopes. Our findings on the induction and maintenance of high-functionality polyclonal T cell repertoires shed light on T cell quality as a neglected criterion in the assessment of vaccine immunogenicity. ### Competing Interest Statement The authors have declared no competing interest.

Recently, I had conversations with 2 people who turned out to be vaccine skeptics. They stopped getting #COVID vaccines after their first jab or two. So, I told them about the 30+ year history behind mRNA vaccine development. That it has been (and continues to be) worked on for treating cancer as well as for other diseases. And that mRNA vaccines were part-way developed for #SARS during the 2002-2004 outbreak (but work stopped because the infection petered out for various reasons) and for Zika. And that when the pandemic came along, most of the pieces of for creating an #mRNA #vaccine for COVID were already in place -- which is why the the vaccines came out relatively quickly. And that they underwent clinical trials before they were approved for release.
Both conversations ended with "Wow, I didn't know any of that. You've given me something to think about."
I'll take it as a win.
Sometimes it's #history more than #science that can help get a message across.

Sources:
1.Timeline: niaid.nih.gov/diseases-conditi
2. One of the best summaries of the mRNA vaccine and its history. statnews.com/2020/11/10/the-st

#publichealth @medmastodon #medmastodon #IDmastodon

Had a mild #COVID19 infection?
Doesn’t mean it’s mild.

#SARS-Cov-2 can behave like HIV or Polio. It can cause internal damage long after apparent recovery.

Mild initial infection does not = mild disease.

Multiple studies show this. #LongCovid
nbcnews.com/health/health-news

NBC News · Long Covid: Even mild Covid is linked to damage to the brain months after infectionBy Benjamin Ryan

"What if the virus behind #COVID-19 did more than just infect cells, but also altered them in a way that could worsen heart disease? A recent study explores this question by investigating how the spike protein of #SARS-CoV-2, the virus causing COVID-19, contributes to heart failure through a process called cellular senescence (when cells lose the ability to replicate themselves). The study uncovers how this viral protein can provoke long-lasting changes in heart cells, even in the absence of active viral infection.
Scientists discovered that the spike protein of SARS-CoV-2, even without the presence of the virus itself, can cause heart cells to become superglued together into larger structures known as syncytia. These globs of cells go into a state of cellular senescence, where the cells stop dividing & begin to secrete inflammatory molecules. This senescent state is characterized by changes that can exacerbate heart failure."
The findings appear in the journal PLOS Pathogens doi.org/10.1371/journal.ppat.1

journals.plos.orgSARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failureAuthor summary In this paper, we directly linked SARS-2-S-triggered syncytium formation in the absence of infection with the ensuing induction of cellular senescence and its pathophysiological contribution to heart failure. We propose that both SARS-2-S expression and SARS-2-S protein internalization were sufficient to induce senescence in nonsenescent ACE2-expressing cells. This is important because of the persistent existence of SARS-2-S or extracellular vesicles containing SARS-2-S during the post-acute stages of SARS-CoV-2 infection in human subjects. In searching for the underlying molecular mechanisms determining syncytial fate, the formation of functional MAVS aggregates dependent on RIG-I was observed at an early stage during fusion and regulated the anti-death to senescence fate of SARS-2-S syncytia through the TNFα-TNFR2 axis. We also found impaired cardiac metabolism in SARS-2-S syncytia induced by condensed WNK1. However, syncytium formation or cellular senescence observed with the wild-type fusogenic S protein does not occur with the spike proteins produced by currently approved COVID-19 mRNA vaccines. Importantly, SARS-2-S-exacerbated heart failure could be largely rescued by WNK1 inhibitor, anti-syncytial drug or senolytic agent. Together, we suggest that rescuing metabolism dysfunction in senescent SARS-2-S syncytia should be taken into consideration in individuals with post-acute sequelae of COVID-19 (PASC).

Interessiert euch, wie hoch euer Risiko für #LongCOVID ist? Die private Organisation Immunisation Coalition hat gemeinsam mit weiteren australischen Universitäten einen Kalkulator online gestellt. Hier könnt ihr euer individuelles #Risiko abschätzen:

corical.immunisationcoalition.

#SARS-CoV-2 #Post-COVID #PACS

corical.immunisationcoalition.org.auCovid Risk Calculator | Immunisation CoalitionAustralian Covid Risk Calculator by the Immunisation Coalition

I wonder if there were parallels to this pattern of wildlife infections by humans during past epidemics. The world is much more toxic, now, everything's immune system is depleted.
"The #covid_19 virus is widespread amongst wildlife in the United States.
The greatest exposure was found in animals near hiking trails and high-traffic public areas, suggesting that the virus passed from humans to wildlife. Genetic testing of wild animals confirmed both the presence of #SARS-CoV-2 and the existence of unique viral mutations with lineages that closely matched variants circulating in humans at the time, further supporting the idea of human-to-animal transmission.
Researchers identified the virus in deer mice, Virginia opossums, raccoons, groundhogs, Eastern cottontail rabbits, & Eastern red bats.
One possible COVID source is contaminated wastewater, but they think it’s more likely that trash bins & food waste are the main sources."
forbes.com/sites/grrlscientist

Forbes · COVID-19 Is Widespread In ‘Common Backyard Wildlife’ In USBy GrrlScientist
Continued thread

Dr. Chen Chien-Jen was Taiwan’s Premier until last month. He’s also an epidemiologist. He spoke to Elaine Lin of @timkmak’s Counteroffensive about how, because of China’s opposition, Taiwan has been excluded from almost all international organizations, including the World Health Organization.

Dr. Chen was leading the country’s health department at the time of the SARS outbreak in 2003, and witnessed firsthand the devastating effect of this exclusion.

flip.it/jPE6Cr

The Counteroffensive with Tim Mak · China’s war against Taiwan at the World Health OrganizationBy Elaine Lin

**Does HIPAA Even Exist for Large Corporations? -- PART 2**

Today I got my official reply to my HHS Office of Civil Rights complaint of 5/3/24 against CVS for violating HIPAA regulations. The minor and rather impressive miracle here is that I got a signed letter from an attorney in only 17 days with relevant regulations and interpretations attached. Good so far.

The result was that they are not going to pursue a formal complaint -- instead they are going to "resolve this matter informally through the provision of technical assistance to CVS."

HHS OCR points out that "a covered entity must maintain reasonable and appropriate administrative, technical, and physical safeguards to prevent intentional or unintentional use or disclosure of PHI in violation of the Privacy Rule and to limit its incidental use and disclosure pursuant to otherwise permitted or required use or disclosure.... Further, under the Security Rule, with certain exceptions, the use of encryption is addressable; i.e., not mandatory." [red emphasis mine]

HHS further states under Reasonable Safeguards that "It is not expected that a covered entity’s safeguards guarantee the privacy of protected health information from any and all potential risks. Reasonable safeguards will vary from covered entity to covered entity depending on factors, such as the size of the covered entity and the nature of its business."

If HHS OCR actually in fact offers this technical assistance in a meaningful way, that WOULD satisfy my complaint -- not that anyone is asking me. This was almost certainly a stupid screw-up by someone in CVS Info Tech programming the canned computer "after visit summary" process to send out way too much information in unencrypted format to people who received a COVID booster at a CVS. If CVS STOPS doing this, I'm good.

To recap -- I received an after-visit summary not only listing what COVID booster med I received, but also my DOB, home address, and all the answers to my screening questionnaire including my answers to whether or not I have ever had a seizure, a bleeding disorder, am currently pregnant, am immunocompromised (including from cancer), have a history of myocarditis, and many other questions.

I will waste my time writing HHS OCR back to thank them and to remind them that to the best of my knowledge I never signed a release for disclosure (which apparently has no legal bearing here?), and that in this new age of AI every major tech company is incorporating AI into EVERYTHING. If I had a Gmail account, Google would have all my medical information from this CVS after visit summary email and likely would be utilizing AI to monetize it in some way.

I suppose the good news here for small psychotherapy practices is that if this is close to acceptable practice for even a giant company like CVS, then maybe we have little to worry about when it comes to client privacy. Heck -- why not just email client PHI to them without getting releases first? Why have encrypted client portals for communication?

-- Michael

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
**Does HIPAA Even Exist for Large Corporations? -- PART 1**

I don't care if anyone knows I just got a COVID vaccine. Most people don't care.

However, CVS Pharmacy just sent me an after-visit report across unencrypted Internet to my email address.

The form included such fields as:
-- My Full Name
-- **DATE OF BIRTH!**
-- My Full Home Address
-- Medication Administered
-- Date and Time of Appointment
-- Name of Pharmacist I saw
-- Name of Doctor at CVS overseeing it all
-- Name and Address of my Primary Care Doctor

Also:
-- All the answers to my *screening questionnaire!* including my yes/no answers to multiple medical conditions such as heart problems, immunocompromise, seizures & other brain problems, and pregnancy.

So many things wrong here. This is almost enough information for identity theft (lacking only SSN). It gives away LOTS of my medical information. If I had a Gmail email address, Google would now have all this information. What if I was a pregnant female in the southern USA where Attorney Generals are starting to track state of pregnancy for later prosecution if women go out-of-state for abortions or have a suspicious (to them) miscarriage?

**How does CVS get away with this when smaller medical offices have to be so careful?**

Michael Reeder, LCPC

#AI #EHR #medicalnotes #progressnotes #healthcare #patientportal #HIPAA #dataprotection #infosec @infosec #doctors #hospitals #CVS #COVID #sars-cov-2 #longcovid #severecovid#covidisnotover #pharmacy #vaccine

Replied in thread

@pixplz They could have been safe(r).

Here’s a link to the Boston Public school ventilation monitoring system. Some of the schools you can click on and see the air quality in each classroom at any time of day or night, some of them it looks more like they aggregated the results. But either way it’s pretty impressive.

bostonschoolsiaq.terrabase.com

Also the Death Panel Pod had a great episode where they talked about how Boston Public schools got some great data about how well masks worked because of this ventilation system.

After our idiot president decided that vaccinated people didn’t have to wear masks anymore, some of the public schools dropped the masks while some of them kept them. They all kept the ventilation.

The data showed that masks kept people from getting infected even with the ventilation. It was a great episode (they all are really)

I think it was this one but if not it was the one titled “How Liberals Killed Masking”.

podcasts.apple.com/us/podcast/

bostonschoolsiaq.terrabase.comBoston Public Schools Indoor Air Quality
Continued thread

4. Disconect the Impact

Risk is event, its probability times impact.

Attack the event (its seasonal, nothing around now), its probability (its rare!) or its impact (its mild!)

Attacking the impact chops up the risk consequence from the risk probability.

E.g. Ok The probability of infection may be high (2-3 times a year say). So what if there is alot of #SARS floating around? So what if you get it 3 times a year? Its mild, its a cold, you will get over it fast. No big deal, right?

No. The actual impacts occur during both acute infection and post-acute stages. Best evidence says even "mild" infections have long term risk.

Disconnecting the Impact, minimizes the consequences of the risk event and causes you to stop thinking about about taking action.

You end up accepting the risk without question.

Which is, yet again, the point.