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#genetics

13 posts13 participants1 post today
Public
Petra van Cronenburg

“This is a designer dog. This is a genetically modified gray wolf,” says Jacquelyn Gill, a paleoecologist at the University of Maine, who has worked with Shapiro in the past but was not involved in this project. “I have more than 14 Neandertal genes in me, and we wouldn’t call me a Neandertal.” scientificamerican.com/article by @andreatweather.bsky.social‬

Colossal's dire wolf standing outside on grass with trees in the background
Scientific American · The Dire Wolf Isn’t Back—But Here’s What ‘De-Extinction’ Tech Can Actually DoBy Andrea Thompson
#deextinction#DireWolf#Colossal
Public
Ele Willoughby, PhD

Happy birthday to Canadian 🇨🇦 geneticist Irene Ayako Uchida (1917-2013)! In my #linocut Uchida is shown surrounded by chromosones, with anomalies (shown with pink arrows) due to radiation exposure, based on one of her research papers. A strand of DNA is hidden in the image (as her watchband).⁠
⁠
Uchida didn’t set out to be a scientist. She was studying English literature at UBC, before she was interned 🧵1/n
⁠
#printmaking #sciart #genetics #cytology #DNA #histstm #WomenInSTEM #chromosomes

Linocut portrait of geneticist Irene Ayako Uchida (handsome, middle age woman of Japanese heritage with curly hair with a white streak on her right temple, with an open, thoughtful face) leaning on folded arms in a white button down shirt with a small watch with double-helix watchband on her wrist, in dark teal-grey ink. She is surrounded by chromosomes in gold, from one of her papers. The anomalous ones are pointed out with small pink arrows.
Public
Frankie ✅

No, the dire wolf has not been brought back from extinction

Colossal Biosciences claims three pups born recently are dire wolves, but they are actually grey wolves with genetic edits intended to make them resemble the lost species

newscientist.com/article/24754

New Scientist · No, the dire wolf has not been brought back from extinctionBy Michael Le Page
#news#science#health
Public
Wen

I generally find #Naughton well worth a swerve, but I do hope this alerts a few - even just that - people. Straightforward and a warning about releasing your data/information to people who undoubtedley will exploit it. If not now, in the future.

I would never provide genetic information to any commercial - or indeed public organisation without far more safeguards than appear now.

theguardian.com/science/2025/a

The Guardian · Genetic data is another asset to be exploited – beware who has yoursBy John Naughton
#Genetics#Privacy#Explotation
Public
Bibliolater 📚 📜 🖋

🔴 🧬 **Genetic data is an another asset to be exploited – beware who has yours**

John Naughton

“_When 23andMe’s data assets come up for sale the queue of likely buyers is going to be long, with health insurance and pharmaceutical giants at the front, followed by hedge-funds, private equity vultures and advertisers, with marketers bringing up the rear._”

🔗 theguardian.com/science/2025/a

#Science #DNA #Genetics #Data #Biology @science @biology

The Guardian · Genetic data is another asset to be exploited – beware who has yoursBy John Naughton
Public
Marsden

"People first noticed the unusual fur patterns ... in three cats in central Finland in 2007. In 2019, researchers at the University of Helsinki reached out to Anderson, a specialist in feline genetics, after learning about another “Finnish mutation” cat.
...
When DNA testing on the cats turned out to be negative for all the gene variants already known to affect white colouring in cat coats, the researchers decided to dig deeper."

#Science #Genetics #Cats #salmiak

newscientist.com/article/24313

New Scientist · Genetic mutation gives cats a 'salty liquorice' coat colourBy Christa Lesté-Lasserre
Public
Bibliolater 📚 📜 🖋

🔴 **Long-term hunter-gatherer continuity in the Rhine-Meuse region was disrupted by local formation of expansive Bell Beaker groups**

“_We document an exception to this pattern in the wider Rhine-Meuse area in communities in the wetlands, riverine areas, and coastal areas of the western and central Netherlands, Belgium and western Germany, where we assembled genome-wide data for 109 people 8500-1700 BCE. Here, a distinctive population with high hunter-gatherer ancestry (∼50%) persisted up to three thousand years later than in continental European regions, reflecting limited incorporation of females of Early European Farmer ancestry into local communities._”

Olalde, I. et al. (2025) 'Long-term hunter-gatherer continuity in the Rhine-Meuse region was disrupted by local formation of expansive Bell Beaker groups,' bioRxiv (Cold Spring Harbor Laboratory) [Preprint]. doi.org/10.1101/2025.03.24.644.

#Preprint #Science #Biology #Genetics #Archaeology #Archaeodons #Anthropology #Europe @archaeodons

bioRxiv · Long-term hunter-gatherer continuity in the Rhine-Meuse region was disrupted by local formation of expansive Bell Beaker groupsThe first phase of the ancient DNA revolution painted a broad-brush picture of European Holocene prehistory, whereby 6500-4000 BCE, farmers descending from western Anatolians mixed with local hunter-gatherers resulting in 70-100% ancestry turnover, then 3000-2500 BCE people associated with the Corded Ware complex spread steppe ancestry into north-central Europe. We document an exception to this pattern in the wider Rhine-Meuse area in communities in the wetlands, riverine areas, and coastal areas of the western and central Netherlands, Belgium and western Germany, where we assembled genome-wide data for 109 people 8500-1700 BCE. Here, a distinctive population with high hunter-gatherer ancestry (∼50%) persisted up to three thousand years later than in continental European regions, reflecting limited incorporation of females of Early European Farmer ancestry into local communities. In the western Netherlands, the arrival of the Corded Ware complex was also exceptional: lowland individuals from settlements adopting Corded Ware pottery had hardly any steppe ancestry, despite a characteristic early Corded Ware Y-chromosome. The limited influx may reflect the unique ecology of the region’s river-dominated landscapes, which were not amenable to wholesale adoption of the early Neolithic type of farming introduced by Linearbandkeramik, making it possible for previously established groups to thrive, and creating a persistent but permeable boundary that allowed transfer of ideas and low-level gene flow. This changed with the formation-through-mixture of Bell Beaker using populations ∼2500 BCE by fusion of local Rhine-Meuse people (9-17%) and Corded Ware associated migrants of both sexes. Their expansion from the Rhine-Meuse region then had a disruptive impact across a much wider part of northwest Europe, including Britain where its arrival was the main source of a 90-100% replacement of local Neolithic peoples. ### Competing Interest Statement The authors have declared no competing interest.
Public
Science Updates

When a drug causes an unintended effect, that is an adverse drug reaction (ADR), and they can range from mild to severe. Sometimes, they may even have life-threatening impacts. In the US in 2022 alone, there were more than 1.25 million documented serious ADR events, and almost 175,000 deaths. Some research has shown that the vast majority of people, about 90%, carry some genetic variant that can lead to an ADR.

#genetics #research #science #health #medicine

labroots.com/trending/clinical

LabrootsTesting for 3 Genes May Prevent Many Drug Side Effects | Clinical And Molecular DxWhen a drug causes an unintended effect, that is an adverse drug reaction (ADR); they can range from mild to severe or even life-threatening | Clinical And Molecular Dx
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